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Autoimmune Health Reset Diet: A Scientifically Informed Guide

The concept of an autoimmune health reset diet has been gaining significant attention in the wellness community, offering hope and a proactive approach for those struggling with autoimmune conditions. Dr. Blum's The Immune System Recovery Plan was one of the first plans to outline how to use diet to reverse autoimmune disease. This comprehensive guide dives into the scientific underpinnings of such diets and provides a practical, evidence-based daily meal plan tailored to support autoimmune health.

Understanding Autoimmune Diseases

Autoimmune diseases occur when the body's immune system mistakenly attacks its own cells. Conditions like rheumatoid arthritis, lupus, and multiple sclerosis are among the more than 80 types of autoimmune diseases affecting millions worldwide. While genetics play a role, environmental factors, including diet, are believed to significantly influence their development and progression, due to epigenetics. Lifestyle changes can start at any time, don't wait until you have to in order to make healthy choices. 

The Role of Diet in Autoimmune Diseases

Emerging research suggests that certain dietary patterns may exacerbate or alleviate autoimmune symptoms. This is primarily due to the diet's impact on gut health, inflammation, and the immune system.

  1. Gut Health: The gut microbiome plays a crucial role in immune function. Imbalances in gut bacteria have been linked to autoimmune diseases (Vighi et al., 2008). A diet rich in fiber, fermented foods, and diverse plant-based foods can promote a healthy gut microbiome.

  2. Inflammation: Chronic inflammation is a hallmark of autoimmune diseases. Diets high in antioxidants, omega-3 fatty acids, and low in processed foods can reduce inflammation (Calder et al., 2011).

  3. Immune Regulation: Certain dietary components can help modulate the immune system. For instance, vitamin D, found in fatty fish and fortified foods, is essential for immune health and has been linked to a lower risk of autoimmune diseases (Aranow, 2011).

Autoimmune Health Reset Diet: Key Components

Based on these principles, an autoimmune health reset diet emphasizes:

  • Whole Foods: Focus on unprocessed, natural and when possible organic foods. 
  • Anti-Inflammatory Foods: Incorporate foods that combat inflammation like Berries, nuts and seeds, dark leafy greens, fatty fish, olive oil, turmeric and ginger, cruciferous veggies, and legumes. 
  • Gut-Healthy Foods: Include probiotics, prebiotics, and fiber. Fermented foods are wonderful like kimchi, sauerkraut, pickles etc.
  • Elimination of Trigger Foods: Dr. Blum always recommends starting with an elimination diet. Temporarily remove foods that commonly cause sensitivities, like gluten, dairy, and soy.

Evidence-Based Daily Meal Plan

Here’s a sample meal plan incorporating these principles:


  • Healthy Breakfast Protein Shake: Blend spinach, berries, chia seeds, almond milk, and a scoop of plant-based protein powder. This provides antioxidants, omega-3s, and fiber.

Mid-Morning Snack:

  • Carrot and Cucumber Sticks with Butternut Squash Hummus: Offers a healthy dose of gut-friendly fiber and protein.


  • Quinoa Salad with Burmese Tofu: Mix quinoa with grilled chicken, mixed greens, avocado, cherry tomatoes, and a dressing of olive oil and lemon juice. This meal is rich in protein, healthy fats, and antioxidants.

Afternoon Snack:

  • A Handful of Nuts: Almonds or walnuts provide healthy fats and vitamin E, an antioxidant.


  • Baked Salmon with Steamed Broccoli and Sweet Potato: Salmon is high in omega-3 fatty acids, and sweet potatoes are a great source of beta-carotene and fiber.

Evening Snack (if needed):

  • Greek or Coconut Yogurt with Honey and Flaxseeds: For those not sensitive to dairy, Greek yogurt is an excellent probiotic food, and flaxseeds add omega-3s.

Considerations and Adaptations

It’s important to note that individual responses to dietary changes vary. What works for one person may not work for another. Keeping a food diary and working with a healthcare provider or a dietitian can help identify personal triggers and tailor the diet to individual needs.

An autoimmune health reset diet, grounded in scientific evidence, offers a promising approach to managing autoimmune conditions. By focusing on whole, anti-inflammatory, and gut-healthy foods, and eliminating potential triggers, individuals can proactively support their immune system and overall health. Remember, this dietary approach should complement medical treatment and be part of a comprehensive approach to managing autoimmune diseases.


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